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Nishikino, Masaharu; Ishino, Masahiko; Hasegawa, Noboru; Kawachi, Tetsuya; Sato, Katsutoshi*; Numasaki, Hodaka*; Teshima, Teruki*; Oshima, Shinsuke*; Okano, Yasuaki*; Nishimura, Hiroaki*
no journal, ,
Recently, high energy, monochromatic X-rays emanating from laser-produced plasma (LPP) are attracting much attention as a new radiation source indispensable for high energy density physics, bioscience, and material sciences. Aiming at these applications, we have been improving performances of Ka lines emitted from LPP and soft X-ray lasers (XRLs). The monochromaticity is particularly important when X-rays are handled with a narrowband optics or used to selectively excite a specific material involved in matters. In addition, timeduration of such sources is typically an order of picosecond, and it could be comparable or even shorter than recovery time of radiatively-damaged biological cell, so that the LPP source can be a new source for investigating the mechanisms of irradiation survival and death of biological cells. We propose to develop an ultrashort, intense X-ray microbeam system to study the radiobiological effect and the bystander effect.
Sagisaka, Akito
no journal, ,
no abstracts in English
Kondo, Kiminori
no journal, ,
The laser acceleration study has been advanced remarkably. Recently, a stable electron bunch generation is one of a hot topic. In this paper, we will present a successful stabilization of electron bunch generation by laser wakefield accelerator, which has been performed at KPSI in this spring. With Ar gas jet target, a very narrow beam divergence of 5 mrad has been obtained, while the peak energy of the electron energy spectrum was 8MeV. Although the laser acceleration physics were thought to be determined only by a electron plasma density, this experimental results suggests that it has been affected noy only by the electron density, but also by the spieces of gas.
Kado, Masataka; Ishino, Masahiko; Nishikino, Masaharu; Hasegawa, Noboru; Kawachi, Tetsuya; Mizutani, Haruo*; Shinohara, Kunio*
no journal, ,
no abstracts in English
Yogo, Akifumi
no journal, ,
We demonstrate the irradiation effect of laser-accelerated protons induced on human lung cancer cells. 
A549 cells are irradiated with a proton dose of 20 Gy, resulting in a distinct formation of 
-H2AX foci as an indicator 
of DNA double-strand breaks. This is the first result showing that laser-driven ion beams can generate a lethal effect on cancer cells.